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& Adnan, A

In: Harcourt-Brown F CJ, editor

Choosing the right needle for your peptide pen The needle matters more than most people think

While the most toxic antiretroviral drugs (e.g., Efavirenz) are slowly being taken out of the market, more research is still needed to fully discriminate ART toxicity and its contribution to comorbidities observed in HIV-positive patients, especially in the context of aging, which alters both drug kinetics and susceptibility of the host to ART-induced side effects

Individuals with B12 deficiency, which can occur due to dietary restrictions (e.g., vegan or vegetarian diets), gastrointestinal disorders affecting absorption, older age, or certain medical conditions that interfere with B12 absorption